50 mg/kg/day q8hr in divided doses; maximum mg/dose. Chlamydial Infection in Pregnant Women (Off-label) First trimester: mg PO q8hr for 7 days. Dosage Modifications Renal impairment. Mild-to moderate (CrCl ≥30 mL/min): No dosage adjustment necessary. Feb 24, · Usual Adult Dose for Skin or Soft Tissue Infection mg orally every 8 hours or mg orally every 12 hours for 7 days, or for 3 days following resolution of acute inflammation For more severe infections, mg orally every 8 hours or mg orally every 12 hours may be administered.